This tweak allows you to
set up a program that will be run once and then deleted so that it does
not run again unless the entry is re-entered manually. The Runonce key
does remain in the registry for reuse.

[Start] [Run] [Regedit]
Registry Key: HKEY_CURRENT_USER\Software\Microsoft\Windows\CurrentVersion\
Create the Key: Runonce
(The [Runonce] Key you create will remain in the registry for use with a new string value)
Create Data Type: REG_SZ [String Value]
Value Name: [Enter the Name of Program Executable]
Value Data: [Enter the Path to the Program Executable]
Exit Registry and Reboot