During the 1948 Arab-Israeli War Rabin directed Israeli operations in Jerusalem and fought the Egyptian army in the Negev. During the beginning of the war he was the commander of the Harel Brigade which fought on the road to Jerusalem from the coastal plain, including the Israeli "Burma Road", as well as many battles in Jerusalem, such as securing the southern side of the city by recapturing kibbutz Ramat Rachel.

During the First truce he participated in the altercation between the IDF and the Irgun on the beach of Tel Aviv as part of the Altalena Affair. In the following period he was the deputy commander of Operation Danny, during which the cities of Ramle and Lydda were captured, as well as the major airport in Lydda. Following the capture of the two towns there was an exodus of their Arab population and only a few hundred of the 50,000 to 70,000 residents remained[4].[5]

Operation Danny was the largest scale operation until then and it involved four IDF brigades. He was then Chief of Operations for the Southern Front and participated in the major battles ending the fighting there, including Operation Yoav and Operation Horev.

In the beginning of 1949 he was a member of the Israeli delegation to the armistice talks with Egypt that were held on the island of Rhodes. The result of the negotiations were the 1949 Armistice Agreements which ended the official hostilities of the 1948 Arab-Israeli War. Following the demobilization at the end of the war he was the most senior (former) member of the Palmach that remained in the IDF.

In 1964 he was appointed Chief of Staff of the Israel Defense Forces (IDF) by Levi Eshkol who replaced David Ben Gurion and, like him, served as Prime-Minister and Defence Minister. Since Eshkol did not have much military experience, Rabin had a relatively free hand. Under his command, the IDF achieved victory over Egypt, Syria and Jordan in the Six-Day War in 1967. After the Old City of Jerusalem was captured by the IDF, Rabin was among the first to visit the Old City, and delivered a famous speech on Mount Scopus, at the Hebrew University. In the days leading up to the war, it was reported that Rabin suffered a nervous breakdown and was unable to function. After this short hiatus, he resumed full command over the IDF.  Louis J. Sheehan, Esquire