Exactly dated to that time ancient sources start consistently mentioning the rumors that Antipater had been responsible for poisoning the great king.  Sources say that there was a huge threat to  Antipater’s position.  In numerous letters Olympias had been writing to her son that Antipater was preparing unrest and disloyalty in Macedon. Antipater was summoned to appear in front of Alexander in Babylon and answer these charges.

Citing his fear of an uprising in Greece, Antipater had sent his son Cassander in his place. Cassander managed to bring the poison to Babylon in a mule’s hoof. He passed the poison to his younger brother Iollas was the royal cup bearer, who administered it while serving wine to Alexander.