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Facts of Life 

Facts of Life:
Issue Briefings for Health Reporters
Vol. 11, No. 2
February 2006

Different Risk: Race-based Health Care and Medicine 

The Issue

The Facts

Targeted Prevention

Expert Sources

References

The Issue:

Scientists have long noted racial differences in the way patients respond to medicine or suffer from disease, says Dr. Esteban González Burchard, who studies genetic and biologic risk factors at the University of California, San Francisco. The charged nature of race enters discussions about racial differences, such as why white women have higher rates of osteoporosis.

Nature or Nurture?

Pediatrician Matthew M. Davis says, “To say that racial and ethnic identity has nothing to do with clinical care is to have our heads in the sand.”

Davis offers the example of an infant with chronic infections and signs of delayed growth and development.“ If that infant is Asian-American with no history of European heritage, it’s very unlikely that cystic fibrosis is the problem,” Davis said.

“ But if that child is European-American, I’ll do tests for cystic fibrosis much more quickly. Is that considered race-based medicine?”

“ Two groups living in different social contexts can have different responses. That may have nothing to do with underlying genetics,” says David R. Williams, a professor at the University of Michigan. “The gap in health for poor blacks and middle-class blacks is bigger than the black-white health gap.”

Harvard University health policy expert Brian Gibbs believes doctors must appreciate a patient’s background. “The thing to understand is their poor access to care, the influence of poverty, the influence of racism and its toll on how the body responds to those stressors.” Gibbs said.

The Facts:

  • A 2003 study of asthma patients of Mexican and Puerto Rican heritage found that the Puerto Rican patients had poorer response to the asthma control drug Albuterol, a bronchodilator medicine used to improve breathing capacity.1
  • After a November 2004 New England Journal of Medicine study found that BiDil dramatically reduced black patients’ death rate, the combination drug received approval as a heart failure therapy for people who identify themselves as black.2
  • A 2006 New England Journal of Medicine study found that blacks are more vulnerable to lung cancer from smoking cigarettes than whites, Japanese-Americans and Latinos.3
  • A 2005 study that found that black and white girls process salt differently provides clues to racial differences in hypertension and osteoporosis rates. When the adolescents consumed high-salt diets, black girls retained both more calcium and more sodium than their white counterparts.4
  • In March 2005, the cholesterol-lowering drug Crestor was relabeled to urge doctors to lower the starting dose of the medicine for Asian patients to decrease their risk of muscle damage, an uncommon side effect of drugs in the class called statins.
  • Several studies, including a 2001 New England Journal of Medicine


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Comments

  • Lucytorial said on Apr 12, 2008....
    HPV is available here for girls 14 to 30 free of charge.  i think its appropriate.

    health care or racial health care is interesting because of the history of each race not just the current standings. Gotta think more on this though, you're overloading me.
  • hottips4u said on Apr 12, 2008....
    Tobi-Lee  :  I have never been taught to be prejudice.  But my Aunt married a Doctor (practiced general meds long before I was born, he died when I was 20).  He taught us the difference in a more unscientific fashion, simply by pointing out the beauty of a  Red Cardinal and the equal beauty of the Blue Jay.  Both very colorful and of size wild birds.

    But two totally different genetically, and that mixing would weaken each in some fashion and maybe strengthen in another.  The physical changes while evident to any issue perhaps in hue, the far and bigger concern in medical science is the creations of hybrid germs and diseases. 

    The dangers of that, far out weighted the concerns, if any, to the color of their feathers...its their sneezes he would wonder of, as he would say,  and finding away to stop a sniffle before it turns to pneumonia.   He didn't know if they had medicine to fix those kinds of bugs... nor time to learn them quickly enough to help.

    He pointed out that in nature, the follies of the heart can cost a life and far less chances are taken by those not smart enough to read.  Our family always enjoyed conversations in the den, around a table or on a walk.  Even when I couldn't read, I could comprehend.

    I try not to allow my heart to make medical decisions, for that I trust in comprehension of the facts, an informed decision, not an ignorant denial of  the facts.  A selfish decision of my heart today,  may well weaken my daughters heart one day...and I wasn't willing to ask her to pay that price for me.


    Jessi.
  • Lucytorial said on Apr 12, 2008....
    Okay heres a good take one in which I am sure you will understand.

    In Oz there is a massive divide between social equity and medical availability in a whites to blacks ratio.  The unfortunate factor is that the higher death rates in blacks here have come about because the NATURAL diet and medicinals have been all but wiped out and replaced with something their physical systems really cannot cope with.

    For whites it is the sterilized over and over again way in which we live that creates super bugs resistant to antibiotics.  We too could learn from a more natural diet and state of living. I was always taught to lick a wound rather than swab sterilized shit all over it but I can't do that now and nor would I want to if I had kids, the decisions of a parent are always to place the child ahead of any heart choices as you put it, but I wonder though why it is we rely so heavily on medical sterilized solutions than natural ones. I'm off track i know its a huge topic that encompasses such a broad part of society.
  • hottips4u said on Apr 12, 2008....
    Believe me, I think the P-Word is far more dangerous than any other word...

    P for Prejudice.  In medical science fact trumps any perceived prejudice and instead lends itself to the established facts....wherever those facts may lead.  The unwillingness to examine race based medical services is a prejudice people have to overcome if we are to survive, imo....prejudice is not genetic, its ignorant.

    Jessi.
  • lfbno7 said on Apr 13, 2008....
    Medical peer review journals like JAMA and New England Journal of Medicine come up with all kinds of gems.
  • Lucytorial said on Apr 13, 2008....
    interesting, actually Jessi, thanks for deleting that shit... I shouldn't have said anything sorry hon.

    Ifbno... you sound like you read a lot.

    *-}
  • lfbno7 said on Apr 13, 2008....
    yeah, i'm always reading something or other
  • Lucytorial said on Apr 13, 2008....
    I guessed that... actually I'm going to check up on a few things... use my fingers to do do the walking as they say
  • hottips4u said on Apr 13, 2008....
    I read pretty widely and all the better if it has some meat to it, I enjoy this site as well as one that Mr. 7 mentioned above.  For Law the Columbia Law Review, Nexus holds a fair reporter by by far the west law reviews are much more captivating in opinionated cross sections of reviewed cases and issues.  Love seeing the principles applied most often with an ounce of logic as the hold ; I enjoy good energy reading material in any event.  Medical advancements, practices and issues are no less captivating where logic sometimes is crippled and a white elephant, imo.

    jess. 
  • hottips4u said on Apr 13, 2008....
    Marketing Questions "Evade" Race Based Medicine.  Another venue to be considered ; educating the masses.

    Please consider, if you will, vis :

    Last week Jim Edwards of BrandWeek reported on the lackluster sales of NitroMed�s flagship medication, BiDil. This drug, developed for “self-identified” African American patients with heart failure, has been a disappointment. Last quarter it only racked up $3.2 million in sales.

    BiDil received a great deal of publicity when it was launched because it was the first drug approved by the FDA for the treatment of a specific racial group. Edwards suggests that BiDil’s woes cast “doubts on race-based medicine.” He argues this is because blacks may not be as black (genetically) as many may think.

    John Mack, who writes Pharma Marketing Blog, disagrees. He blames NitroMed’s failed marketing campaign for BiDil’s woes. He says that the real problem with BiDil sales may “have more to do with inadequate or ineffective marketing than with less-black-than-you-think genes. It is notoriously difficult to market to minorities and I don’t believe the pharmaceutical industry knows how to do it well or invests enough time or effort figuring out how to do it. You don’t see, for example, very many industry conferences devoted to the subject.”

    I know at least one person who would agree. In an interview I conducted with noted researcher Dr. George Bakris, who has done a lot of work with minority populations, Bakris gave the pharmaceutical industry a D on its communications efforts. He believes “drug firms spend more time educating on the product rather than the disease.”

    While their arguments about the failure of BiDil are compelling, neither Edwards or Mack are correct. BiDil failed because it is simply a new formulation of two generic medications with a tedious dosing schedule. Dr. Keith Ferdinand, who helped to study BiDil, had this to say when I asked him whether marketing was to blame for BiDil’s poor performance:

    “I do not believe that the slow uptake of BiDil (isosorbide dinitrate/hydralazine HCl) can be attributed to weak or inappropriate marketing. Perhaps clinicians were reluctant to use a branded medication when generics are available. Another barrier may have been the fact that patients must take the medication three times per day when they already have complex medical regimens.”

    There you have it. Despite compelling clinical evidence and pressure from the NAACP, NitroMed has not been able to sell BiDil because it is hard to convince physicians (and insurers) to use a medication that has an equally effective generic counterpart. The company is currently developing an extended release, once daily formulation of BiDil. It remains to be seen whether the drug will be approved or successful.

    Rather than focusing on race or marketing, BiDil’s failure can be traced to economics 101. It’s all about price.


  • hottips4u said on Apr 13, 2008....
    Even the results of this study herein below indicates that despite a populace being unwilling to see beyond race as a position or a status of superiority, every race will suffer the consequences, imo.  

    Even behind the scenes, or perhaps rather right out in the open (since most heads are stuffed in the sand if "race" is mentioned...oh my) ; "I just want more accurate specific treatment based upon genetic maps and appropriate cocktails, formulated for specific genetic codes per viruses, pulmonary blueprints accurately individualized based upon race specific & individualized applications rather than the one size fitz most theology of practiced medicine today," and,
    thats my opinion.

    Consider :  Insurance/Cost/Position :



    Treatment of Chest Pain Patients Differs by Race, Gender, Insurance

    Researchers at the Medical College of Wisconsin in Milwaukee and Johns Hopkins University found that race, gender and insurance differences factor strongly in the evaluation of patients with chest pain seen in emergency departments.

    The study, conducted by Liliana E. Pezzin, PhD, Associate Professor of Medicine at the Medical College, along with co-investigators Gary B. Green, MD, MPH, and Penelope Keyl, PhD, at Johns Hopkins, appeared recently in Academic Emergency Medicine.

    Chest pain is the most common initial symptom in patients diagnosed with coronary artery disease. Tests such as electrocardiography, chest radiography as well as oxygen saturation monitoring and cardiac monitoring are non-invasive and useful in diagnosing the disease. The study found that these tests are applied differently based on patients' race, gender and insurance.

    Researchers drew on data compiled by the National Hospital Ambulatory Health Care Survey of Emergency Departments (NHAMCS-ED), from 1995 to 2000, for patients 30 years old or older presenting with chest pain. The retrospective study used a sample of 7,068 patients which corresponded to 32 million visits nationally throughout the six-year period.

    They found that the rate of visits to emergency departments by patients presenting with chest pain increased in the six-year period, and that race, gender and insurance differences were factors in the type of care patients received at emergency departments.

    Overall, African American males were 25 to 30% less likely to receive any of the tests than non-African American males.

    Use of all forms of diagnostic testing and monitoring, with the exception of oxygen saturation monitoring, decreased among male African American patients over the six-year period. Electrocardiography decreased more than 16% among male African American patients, and they were 26% less likely to be placed on cardiac monitoring in 2000 than they were in 1995.

    Gender was also an issue in determining what tests are administered for patients presenting with chest pain. African American women were approximately 5% less likely to have electrocardiography tests than non-African American men.

    African American women were also 17% less likely to undergo cardiac monitoring, 14% less likely to have oxygen saturation monitoring, and 6% less likely to have chest radiography tests than non-African American men. Similarly, the rate of testing was lower for non-African American women than it was for non-African American men.

    Insurance type was also proven to have a significant role in the administration of tests. Patients covered by forms of insurance other than commercial insurance were approximately 13% less likely to undergo electrocardiography. Additionally, patients covered by these forms of insurance were almost 21% less likely to be placed on cardiac monitoring, 23% less likely to have oxygen saturation measured, and more than 13% less likely to receive chest radiography than patients covered by commercial insurance.

    The study also found that approximately 82% of commercially insured non-African American men received electrocardiography testing when presenting with chest pain in 2000. This is nearly a 27% higher proportion than uninsured African American men, and a 31% higher proportion than African American men covered by non-commercial forms of insurance.

    The study was funded, in part, by a grant from the Agency for Healthcare Research and Quality.

    Article Created: 2007-06-12
    Article Updated: 2007-06-12


    Each year, Medical College of Wisconsin physicians care for more than 180,000 patients, representing nearly 500,000 patient visits. Medical College physicians practice at Children's Hospital of Wisconsin, Froedtert Memorial Lutheran Hospital, the Milwaukee VA Medical Center, and many other hospitals and clinics in Milwaukee and southeastern Wisconsin.


  • hottips4u said on Apr 13, 2008....
    RACE BASED MEDICINE IS A PUBLICLY " KNOWN " TABOO.... card table conversation... hottips4u.  

    It kills not to acknowledge it.  Its 2008...craw out of your caves.

    Consider :  

    HIV / AIDS News

    'National Silence' On Sexual Behavior, Race, Poverty Contributes To High Rates Of HIV, Other STIs, Opinion Piece Says

    Main Category: HIV / AIDS
    Also Included In: Sexual Health / STDs
    Article Date: 24 Mar 2008 - 5:00 PDT

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    The "national silence" on issues such as sexual behavior, race and poverty has contributed to the high rate of HIV and other sexually transmitted infections among teenagers in the U.S., Robert Fullilove, associate dean at Columbia University's Mailman School of Public Health, Adaora Adimora, associate professor of medicine at the University of North Carolina-Chapel Hill, and Peter Leone of the North Carolina Division of Public Health write in a Washington Post opinion piece.

    According to the authors, a CDC study released earlier this month that found that about 25% of U.S. girls and young women ages 14 to 19 have at least one of four common STIs is "already old" news for people who work in public health. They add that public health workers "fear this latest study will have its 15 minutes in the spotlight and also fade from view," just like a similar study released 10 years ago by the Institute of Medicine did. The "taboo" of talking about sexual behavior, poverty and race is one "obvious reason" that rates of STIs remain high, the authors write, adding, another is "that the incidence of [STIs], particularly HIV, is concentrated in poor, segregated neighborhoods that are characterized by high rates of incarceration." The "shift" in marriage and courtship patterns that results from men being incarcerated, as well as an increase in the number of "multiple concurrent sexual partnerships," also are contributing to the problem, according to the authors.

    HIV/AIDS and other STIs cost the U.S. "tens of billions of dollars" annually, "but with the exception of HIV infection, [STIs] remain the elephant in the room when it comes to the national conversation about health and health care," the authors write. They add, "We can no longer have effective [STI] prevention campaigns in poor communities of color if they treat one person at a time or ignore social conditions underpinning high rates of HIV and other" STIs. "Simply put, we will never rid the U.S. of HIV and other [STIs] if our only weapon is medical treatment," the authors write, concluding, "And if we are unable to engage in a national dialogue about the sexual health of our youths and the social dynamics that drive [STIs], this epidemic will go largely ignored, and many more lives will be lost" (Fullilove et al., Washington Post, 3/21).

    Reprinted with kind permission from http://www.kaisernetwork.org. You can view the entire Kaiser Daily Health Policy Report, search the archives, or sign up for email delivery at http://www.kaisernetwork.org/dailyreports/healthpolicy. The Kaiser Daily Health Policy Report is published for kaisernetwork.org, a free service of The Henry J. Kaiser Family Foundation© 2005 Advisory Board Company and Kaiser Family Foundation. All rights reserved.

    ______________________________


    That should give ya fodder to gnaw on.......

    { racial medical ignorance kills : jessi }....  thats my opinion.

    and Yours  Is  ??

    Maybe its time to consider one,.....ya think  ??

    Hottips4u

    jessi.




  • hottips4u said on Apr 21, 2008....
    More Butters than I likes for me popcorn even...hehe

    jessi.

Comment on "Get Over It ~ Scientific Fact ~ Dump Prejudice"


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